Acetyl Hexapeptide - 8 (Argireline)

Acetyl Hexapeptide-8, popularly known as Argireline, is a peptide compound often dubbed “Botox in a bottle.” It is widely used in anti-aging skincare for its unique ability to reduce facial tension and minimize the appearance of expression lines and wrinkles. By targeting the same protein complex involved in muscle contraction, it offers a gentle, non-invasive alternative to injectable treatments, perfect for those seeking smoother skin without needles.

INCI Name: Acetyl Hexapeptide-8

Molecular Formula: C₃₄H₆₀N₁₄O₁₂S

Alternate Names: Argireline,  Acetyl Hexapeptide-3, Botox-like peptide

Purity of the Ingredient: 99%

Country of Origin: India

Benefits and Uses

• Reduces the depth of expression lines and wrinkles
• Especially effective on forehead and around eyes ("crow’s feet")
• Provides a gentle tightening effect without harsh chemicals
• Can be used in daily anti-aging formulations
• Ideal for all skin types, especially mature skin

How It Works

• Inhibits neurotransmitter release at neuromuscular junctions, reducing muscle movement
• Relaxes facial tension responsible for fine lines
• Mimics the action of Botox but without injections
• Best used consistently for cumulative smoothing effects

pH and Ideal Temperature Range for Best Use

• Optimal pH: 5.0 – 6.5
• Ideal Temperature: Add during the cool-down phase (below 40°C / 104°F)

How to Use Argireline for Skincare?

• Recommended usage level: 2% to 10%
• Perfect for serums, eye creams, and anti-wrinkle treatments
• Add to the water-based phase during cool-down (<40°C)
• Can be combined with hyaluronic acid for enhanced plumping
• Always patch test before application